COL26A1 - collagen type XXVI alpha 1 chain Gene

Homo sapiens

Also known as EMI6; EMU2; SH2B; EMID2

Gene ID: 136227 | Gene type: protein coding

About COL26A1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:101,362,388-101,559,024 (from NCBI)

This gene has 3 transcripts (splice variants), 182 orthologues and 37 paralogues. Biased expression in brain (RPKM 3.1), kidney (RPKM 1.3) and 9 other tissues.

Summary

This gene encodes a protein containing an emilin domain and two collagen stretches. This gene may be associated with aspirin-intolerant asthma. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

COL26A1 Products(2)

mRNA	Protein	Name
NM_001278563.3	NP_001265492.1	collagen alpha-1(XXVI) chain isoform 1 precursor
NM_133457.5	NP_597714.2	collagen alpha-1(XXVI) chain isoform 2 precursor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32814053	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COL26A1 Protein Structure

EMI

Collagen

0
100
200
300
400
440 a.a.

Protein Preferred Names

Protein Names

collagen alpha-1(XXVI) chain

EMI domain containing 2

Related Diseases

Diseases

Alias

Acute Ethmoiditis

Acute Ethmoidal Sinusitis	Acute Ethmoid Sinusitis
Ethmoidal Sinus - Acute

Anal Carcinoma In Situ

Carcinoma In Situ Of Anal Canal	Carcinoma In Situ Of Anus
Anal Carcinoma Stage 0	Anal Intraepithelial Neoplasia Grade Iii
Intraepithelial Neoplasia Of Anal Canal, High Grade	Ain - [Anal Intraepithelial Neoplasia] High Grade

Asthma

Chronic Obstructive Asthma	Asthma, Diminished Response To Antileukotriene Treatment In
Bronchial Hyperreactivity	Asthma, Susceptibility To
Asthma, Bronchial	Asthma, Protection Against
Asthma, Nocturnal, Susceptibility To	Nocturnal Asthma
Asthma-Related Traits	Asthma-Related Traits, Susceptibility To
Asthma, Nocturnal	Chronic Obstructive Asthma With Acute Exacerbation
Chronic Obstructive Asthma With Status Asthmaticus	Exercise Induced Asthma
Exercise-Induced Asthma	Bronchial Asthma
Asthma, Exercise-Induced	Idiosyncratic Asthma
Unspecified Asthma With Acute Exacerbation	Asthma, Unspecified, With Stated Status Asthmaticus
Status Asthmaticus Nos	Acute Severe Asthma
Acute Severe Bronchial Asthma	Status Asthma
Status Post Asthmaticus

Asthma, Nasal Polyps, And Aspirin Intolerance

Asthma And Nasal Polyps	Asa Triad
Asthma, Aspirin-Induced, Susceptibility To	Asthma, Aspirin-Induced
Asthma, With Nasal Polyps And Aspirin Intolerance	ANPAI
Aia	Aspirin-Intolerant Asthma
Asthma Aspirin-Induced	Nasal Polyps Asthma And Aspirin Sensitivity
Samter Triad	Asthma With Aspirin Triad Including Nonsteroidal Anti-Inflammatory Activity And Nasal Polyps

Chronic Maxillary Sinusitis

Chronic Antritis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02978	COL26A1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	COL26A1	VGNC	VGNC:81293
Felis catus	COL26A1	VGNC	VGNC:61056
Bos taurus	COL26A1	VGNC	VGNC:52757
Rattus norvegicus	COL26A1	RGD	RGD:1591401
Mus musculus	COL26A1	MGD	MGI:2155345

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