1. Gene
  2. SVOPL - SVOP like Gene

SVOPL - SVOP like Gene

Homo sapiens

Also known as SLC22B5

Gene ID: 136306 | Gene type: protein coding

About SVOPL

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:138,594,285-138,701,362 (from NCBI)

This gene has 8 transcripts (splice variants), 246 orthologues and 22 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is thought to be a member of solute carrier family 22, which includes transmembrane proteins that transport toxins and drugs from the body. This gene is a paralog of the SVOP gene that encodes synaptic vesicle 2-related protein. [provided by RefSeq, Sep 2016]

SVOPL Products(3)

mRNA Protein Name
NM_001139456.2 NP_001132928.1 putative transporter SVOPL isoform 1
NM_001331192.1 NP_001318121.1 putative transporter SVOPL isoform 3
NM_174959.3 NP_777619.1 putative transporter SVOPL isoform 2
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SVOPL Protein Structure

MFS_1

MFS_1: Major Facilitator Superfamily (59 - 298)

Sugar_tr

Sugar_tr: Sugar (and other) transporter (353 - 491)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 492 a.a.
Protein Preferred Names Protein Names

putative transporter SVOPL

SV2 related protein homolog-like

Related Diseases

Diseases Alias
Retinitis Pigmentosa 45

RP45

Retinitis Pigmentosa, Type 45

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris SVOPL VGNC VGNC:51828
Rattus norvegicus SVOPL RGD RGD:1566053
Macaca mulatta SVOPL VGNC VGNC:78224
Mus musculus SVOPL MGD MGI:2444335
Bos taurus SVOPL VGNC VGNC:35499
Felis catus SVOPL VGNC VGNC:65866