MAGEC3 - MAGE family member C3 Gene

Homo sapiens

Also known as HCA2; CT7.2; MAGEC4; MAGE-C3

Gene ID: 139081 | Gene type: protein coding

About MAGEC3

Cytogenetic location: Xq27.2 Genomic coordinates (GRCh38): X:141,838,316-141,897,832 (from NCBI)

This gene has 5 transcripts (splice variants), 466 orthologues and 37 paralogues. Low expression observed in reference dataset.

Summary

This gene is a member of the MAGEC gene family. The members of this family are not expressed in normal tissues, except for testis, and are expressed in tumors of various histological types. The MAGEC genes are clustered on chromosome Xq26-q27. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

MAGEC3 Products(2)

mRNA	Protein	Name
NM_138702.1	NP_619647.1	melanoma-associated antigen C3 isoform 1
NM_177456.2	NP_803251.1	melanoma-associated antigen C3 isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAGEC3 Protein Structure

MAGE

0
100
200
300
400
500
600
643 a.a.

Protein Preferred Names

Protein Names

melanoma-associated antigen C3

MAGE family testis and tumor-specific protein

Related Diseases

Diseases

Alias

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Adult Hepatocellular Carcinoma

Adult Primary Hepatocellular Carcinoma	Adult Hepatoma
Adult Hcc

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07975	MAGEC3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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