PASD1 - PAS domain containing repressor 1 Gene

Homo sapiens

Also known as CT63; CT64; OXTES1

Gene ID: 139135 | Gene type: protein coding

About PASD1

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:151,563,675-151,676,739 (from NCBI)

This gene has 2 transcripts (splice variants), 157 orthologues and 6 paralogues. Restricted expression toward testis (RPKM 11.6).

Summary

This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]

PASD1 Products(1)

mRNA	Protein	Name
NM_173493.3	NP_775764.2	circadian clock protein PASD1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables DNA-binding transcription factor binding	IPI IPI: Inferred from physical interaction	25936801	GOA
enables transcription regulator inhibitor activity	IDA IDA: Inferred from direct assay	25936801	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	25936801	GOA
involved in negative regulation of circadian rhythm	IDA IDA: Inferred from direct assay	25936801	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of Cry-Per complex	IDA IDA: Inferred from direct assay	25936801	GOA
located in nucleus	IDA IDA: Inferred from direct assay	25936801	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

circadian clock protein PASD1

PAS domain containing 1

Related Diseases

Diseases

Alias

B-Cell Lymphoma

Lymphoma, B-Cell	B-Cell Lymphomas
B-Cell Lymphocytic Neoplasm	Lymphoma B-Cell
B-Cell Lymphoma Nos

Diffuse Large B-Cell Lymphoma

Dlbcl	Diffuse Large B-Cell Lymphoma, Not Otherwise Specified
Large B-Cell Diffuse Lymphoma	Lymphoma, Large B-Cell, Diffuse
Dlbcl - [Diffuse Large B-Cell Lymphoma]	Diffuse Large Beta Cell Lymphoma

Lymphoma

Lymphoid Cancer	Lymphomas
Lymphoid Cancers	Lymphoid Neoplasm
Lymphoma Nos	Nhl - [Non-Hodgkin Lymphoma]
Non-Hodgkin Lymphoma	Non-Hodgkin Lymphoma, Nos
Non-Hodgkin Malignant Lymphoma Nos

Adult Oligodendroglioma

Adult Brain Oligodendroglioma	Grade Ii Adult Oligodendroglial Tumor
Oligodendroglioma, Adult

Pilocytic Astrocytoma Of Cerebellum

Cerebellar Pilocytic Astrocytoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10077	PASD1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	PASD1	VGNC	VGNC:44269
Mus musculus	PASD1	MGD	MGI:2685987
Macaca mulatta	PASD1	VGNC	VGNC:75659
Rattus norvegicus	PASD1	RGD	RGD:7496877

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