APOOL - apolipoprotein O like Gene

Homo sapiens

Also known as Mic27; CXorf33; FAM121A; MICOS27; UNQ8193

Gene ID: 139322 | Gene type: protein coding

About APOOL

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:85,003,877-85,093,315 (from NCBI)

This gene has 1 transcript (splice variant), 209 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 7.7), thyroid (RPKM 6.2) and 25 other tissues.

Summary

This gene encodes a protein which contains an apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]

APOOL Products(1)

mRNA	Protein	Name
NM_198450.6	NP_940852.3	MICOS complex subunit MIC27 precursor

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	25764979	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
part of MICOS complex	IDA IDA: Inferred from direct assay	25781180	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	25781180	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

APOOL Protein Structure

ApoO

0
100
200
268 a.a.

Protein Preferred Names

Protein Names

MICOS complex subunit MIC27

AAIR8193

Related Diseases

Diseases

Alias

Combined Oxidative Phosphorylation Deficiency 37

COXPD37

Deafness, X-Linked 7

X-Linked External Auditory Canal Atresia-Dilated Internal Auditory Canal-Facial Dysmorphism Syndrome	DFNX7
X-Linked Deafness 7	Deafness, X-Linked, 7

Barth Syndrome

3-Methylglutaconic Aciduria Type 2	BTHS
Cardioskeletal Myopathy With Neutropenia And Abnormal Mitochondria	Mga Type Ii
Mga2	Mgca2
Mga Type 2	3-Methylglutaconic Aciduria Type Ii
3-Methylglutaconic Aciduria, Type Ii	Mga, Type Ii
3-Methylglutaconicaciduria Type 2	3-Methylglutaconicaciduria Type Ii
Taz Defect	3 Methylglutaconic Aciduria, Type Ii
Dnajc19 Defect	Cardioskeletal Myopathy-Neutropenia Syndrome
X-Linked Cardioskeletal Myopathy And Neutropenia	3-Alpha-Methylglutaconic Aciduria Type 2
Agm2	Cardioskeletal Myopathy-Neutropenia
Invm	Left Ventricular Non-Compaction Isolated X-Linked
Non-Compaction Of Left Ventricular Myocardium Isolated X-Linked	Agammaglobulinemia 2, Autosomal Recessive

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00862	APOOL Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	APOOL	RGD	RGD:1549725
Mus musculus	APOOL	MGD	MGI:1915367
Canis familiaris	APOOL	VGNC	VGNC:38009
Macaca mulatta	APOOL	VGNC	VGNC:97734
Bos taurus	APOOL	VGNC	VGNC:26036

Name
Email *

	Sorry, but the email address you supplied was invalid.