2. Gene
  3. ASB5 - ankyrin repeat and SOCS box containing 5 Gene

ASB5 - ankyrin repeat and SOCS box containing 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ASB-5

Gene ID: 140458 | Gene type: protein coding

About ASB5

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,213,673-176,277,524 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues and 2 paralogues. Biased expression in prostate (RPKM 5.3), urinary bladder (RPKM 4.0) and 6 other tissues.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008]

ASB5 Products(2)

mRNA Protein Name
NM_001410863.1 NP_001397792.1 ankyrin repeat and SOCS box protein 5 isoform 2
NM_080874.4 NP_543150.1 ankyrin repeat and SOCS box protein 5 isoform 1

ASB5 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (74 - 164)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (173 - 263)

SOCS_box

SOCS_box: SOCS box (290 - 329)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 5

SOCS box protein ASB-5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01070 ASB5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ASB5 VGNC VGNC:59961
Rattus norvegicus ASB5 RGD RGD:1565973
Canis familiaris ASB5 VGNC VGNC:38165
Bos taurus ASB5 VGNC VGNC:26198
Mus musculus ASB5 MGD MGI:1923544
Macaca mulatta ASB5 VGNC VGNC:69849