F13b - coagulation factor XIII, beta subunit Gene

Mus musculus

Also known as Cf13b; Cf-13b

Gene ID: 14060 | Gene type: protein coding

About F13b

Summary

This gene encodes subunit B of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit A to form a heterotetrameric protein that circulates in the plasma. During the blood coagulation process, thrombin-mediated proteolytic cleavage of the subunit A results in the dissociation of the encoded protein from the heterotetramer. Male mice lacking the encoded protein exhibit mild fibrosis together with hemosiderin deposits in the heart. [provided by RefSeq, Sep 2015]

F13b Products(1)

mRNA	Protein	Name
NM_031164.2	NP_112441.2	coagulation factor XIII B chain precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	18224415	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in blood coagulation	IMP IMP: Inferred from mutant phenotype	18224415	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

coagulation factor XIII B chain

protein-glutamine gamma-glutamyltransferase B chain

transglutaminase B chain

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04629	F13B Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	F13b	NCBI	NCBI:2165
Canis familiaris	F13b	NCBI	NCBI:490261
Macaca fascicularis	F13b	NCBI	NCBI:102136369
Macaca mulatta	F13b	NCBI	NCBI:711237

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