NANP - N-acetylneuraminic acid phosphatase Gene

Homo sapiens

Also known as HDHD4; C20orf147; dJ694B14.3

Gene ID: 140838 | Gene type: protein coding

About NANP

Cytogenetic location: 20p11.21 Genomic coordinates (GRCh38): 20:25,612,935-25,624,014 (from NCBI)

This gene has 1 transcript (splice variant), 213 orthologues and 1 paralogue. Ubiquitous expression in adrenal (RPKM 2.0), testis (RPKM 1.9) and 25 other tissues.

Summary

Enables N-acylneuraminate-9-phosphatase activity. Involved in N-acetylneuraminate biosynthetic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

NANP Products(1)

mRNA	Protein	Name
NM_152667.3	NP_689880.1	N-acylneuraminate-9-phosphatase

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables N-acylneuraminate-9-phosphatase activity	IDA IDA: Inferred from direct assay	16237198	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in CMP-N-acetylneuraminate biosynthetic process	IMP IMP: Inferred from mutant phenotype	31121216	GOA
involved in N-acetylneuraminate biosynthetic process	IDA IDA: Inferred from direct assay	16237198	GOA
involved in glycosylation	IMP IMP: Inferred from mutant phenotype	31121216	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NANP Protein Structure

HAD_2

0
100
200
248 a.a.

Protein Preferred Names

Protein Names

N-acylneuraminate-9-phosphatase

Neu5Ac-9-Pase

Related Diseases

Diseases

Alias

Balanoposthitis

Balanitis Due To Infection

Intracranial Abscess

Abscess Of Brain	Brain Empyema
Cranial Abscess	Intracerebral Abscess
Cerebral Abscess	Cerebral Embolic Abscess
Cerebral Pyogenic Abscess	Septic Brain Infection
Temporosphenoidal Abscess	Ventricular Empyema
Intracranial Suppuration	Intracranial Vein Sinus Abscess

Benign Essential Hypertension

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09024	NANP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	NANP	MGD	MGI:1914561
Bos taurus	NANP	VGNC	VGNC:31877
Macaca mulatta	NANP	VGNC	VGNC:74971
Rattus norvegicus	NANP	RGD	RGD:1306009

Name
Email *

	Sorry, but the email address you supplied was invalid.