ASB15 - ankyrin repeat and SOCS box containing 15 Gene

Homo sapiens

Gene ID: 142685 | Gene type: protein coding

About ASB15

Cytogenetic location: 7q31.32 Genomic coordinates (GRCh38): 7:123,567,008-123,639,481 (from NCBI)

This gene has 6 transcripts (splice variants), 271 orthologues and 7 paralogues. Biased expression in heart (RPKM 6.0), kidney (RPKM 2.1) and 2 other tissues.

Summary

This gene encodes a member of the suppressor of cytokine signaling box superfamily. The proteins in this superfamily participate in the ubiquitin-proteasome system for the degradation of proteins in the cell cycle and signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

ASB15 Products(2)

mRNA	Protein	Name
NM_001290258.2	NP_001277187.1	ankyrin repeat and SOCS box protein 15
NM_080928.4	NP_563616.3	ankyrin repeat and SOCS box protein 15

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ASB15 Protein Structure

Ank_2

SOCS_box

0
100
200
300
400
500
588 a.a.

Protein Preferred Names

Protein Names

ankyrin repeat and SOCS box protein 15

epididymis secretory sperm binding protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01064	ASB15 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ASB15	RGD	RGD:727860
Felis catus	ASB15	VGNC	VGNC:69352
Bos taurus	ASB15	VGNC	VGNC:26192
Canis familiaris	ASB15	VGNC	VGNC:38159
Macaca mulatta	ASB15	VGNC	VGNC:80795
Mus musculus	ASB15	MGD	MGI:1926160

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