2. Gene
  3. ASB15 - ankyrin repeat and SOCS box containing 15 Gene

ASB15 - ankyrin repeat and SOCS box containing 15 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 142685 | Gene type: protein coding

About ASB15

Cytogenetic location: 7q31.32 Genomic coordinates (GRCh38): 7:123,567,008-123,639,481 (from NCBI)

This gene has 6 transcripts (splice variants), 271 orthologues and 7 paralogues. Biased expression in heart (RPKM 6.0), kidney (RPKM 2.1) and 2 other tissues.

Summary

This gene encodes a member of the suppressor of cytokine signaling box superfamily. The proteins in this superfamily participate in the ubiquitin-proteasome system for the degradation of proteins in the cell cycle and signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

ASB15 Products(2)

mRNA Protein Name
NM_001290258.2 NP_001277187.1 ankyrin repeat and SOCS box protein 15
NM_080928.4 NP_563616.3 ankyrin repeat and SOCS box protein 15
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ASB15 Protein Structure

Ank_2

Ank_2: Ankyrin repeats (3 copies) (115 - 207)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (214 - 297)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (313 - 407)

SOCS_box

SOCS_box: SOCS box (534 - 576)

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  • 588 a.a.
Protein Preferred Names Protein Names

ankyrin repeat and SOCS box protein 15

epididymis secretory sperm binding protein

ASB15 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
ASB15 Q8WXK1 GPSM3 Homo sapiens Q9Y4H4
Validated Y2H
32296183
Intra
ASB15 Q8WXK1 ZNF587 Homo sapiens Q96SQ5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01064 ASB15 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ASB15 RGD RGD:727860
Felis catus ASB15 VGNC VGNC:69352
Bos taurus ASB15 VGNC VGNC:26192
Canis familiaris ASB15 VGNC VGNC:38159
Macaca mulatta ASB15 VGNC VGNC:80795
Mus musculus ASB15 MGD MGI:1926160