ASB14 - ankyrin repeat and SOCS box containing 14 Gene

Homo sapiens

Gene ID: 142686 | Gene type: protein coding

About ASB14

This gene has 3 transcripts (splice variants), 264 orthologues and 7 paralogues. Ubiquitous expression in heart (RPKM 1.8), bone marrow (RPKM 1.0) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2008]

ASB14 Products(2)

mRNA	Protein	Name
NM_001142733.3	NP_001136205.2	ankyrin repeat and SOCS box protein 14 isoform 1
NM_130387.5	NP_569058.1	ankyrin repeat and SOCS box protein 14 isoform 2 precursor

ASB14 Protein Structure

Ank_2

SOCS_box

0
100
200
300
400
500
587 a.a.

Protein Preferred Names

Protein Names

ankyrin repeat and SOCS box protein 14

ankyrin repeat domain-containing SOCS box protein Asb-14

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01063	ASB14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-136962	ASB-14		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ASB14	RGD	RGD:1596812
Bos taurus	ASB14	VGNC	VGNC:26191
Felis catus	ASB14	VGNC	VGNC:69351
Mus musculus	ASB14	MGD	MGI:2655107
Macaca mulatta	ASB14	VGNC	VGNC:84237
Canis familiaris	ASB14	VGNC	VGNC:38158

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