SYT9 - synaptotagmin 9 Gene

Homo sapiens

Gene ID: 143425 | Gene type: protein coding

About SYT9

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:7,238,778-7,469,043 (from NCBI)

This gene has 3 transcripts (splice variants), 281 orthologues and 31 paralogues. Biased expression in brain (RPKM 1.0), adrenal (RPKM 0.5) and 7 other tissues.

Summary

Predicted to enable several functions, including calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Predicted to be involved in calcium-ion regulated exocytosis; cellular response to calcium ion; and regulation of secretion by cell. Predicted to be located in clathrin-coated endocytic vesicle membrane. Predicted to be active in hippocampal mossy fiber to CA3 synapse; plasma membrane; and secretory vesicle. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

SYT9 Products(1)

mRNA	Protein	Name
NM_175733.4	NP_783860.1	synaptotagmin-9

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYT9 Protein Structure

0
100
200
300
400
491 a.a.

Protein Preferred Names

Protein Names

synaptotagmin-9

synaptotagmin IX

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14121	SYT9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SYT9	VGNC	VGNC:49736
Mus musculus	SYT9	MGD	MGI:1926373
Rattus norvegicus	SYT9	RGD	RGD:621169
Macaca mulatta	SYT9	VGNC	VGNC:82251
Bos taurus	SYT9	VGNC	VGNC:35545
Felis catus	SYT9	VGNC	VGNC:65904

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