1. Gene
  2. NCAN - neurocan Gene

NCAN - neurocan Gene

Homo sapiens

Also known as CSPG3

Gene ID: 1463 | Gene type: protein coding

About NCAN

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:19,211,958-19,252,233 (from NCBI)

This gene has 4 transcripts (splice variants), 278 orthologues and 7 paralogues. Restricted expression toward brain (RPKM 74.5).

Summary

Neurocan is a chondroitin sulfate proteoglycan thought to be involved in the modulation of cell adhesion and migration.[supplied by OMIM, Jul 2002]

NCAN Products(1)

mRNA Protein Name
NM_004386.3 NP_004377.2 neurocan core protein precursor

NCAN Protein Structure

V-set

V-set: Immunoglobulin V-set domain (45 - 145)

Xlink

Xlink: Extracellular link domain (159 - 254)

Xlink

Xlink: Extracellular link domain (260 - 356)

Lectin_C

Lectin_C: Lectin C-type domain (1107 - 1210)

Sushi

Sushi: Sushi repeat (SCR repeat) (1215 - 1271)

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  • 1321 a.a.
Protein Preferred Names Protein Names

neurocan core protein

chondroitin sulfate proteoglycan 3 (neurocan)

NCAN Antibodies

Cat. No. Product Name Application Reactivity
HY-P83101 Neurocan Antibody (YA2846) WB, IHC-P, IP Human

Related Diseases

Diseases Alias
Bipolar Disorder

Bipolar Depression

Manic Disorder

Depression, Bipolar

Bipolar Disorder Manic Phase

Depressive-Manic Psych.

Manic Bipolar Affective Disorder

Manic Bipolar I Disorder

Manic Depression

Manic Depressive Disorder

Mixed Bipolar Disorder

Bipolar Affective Disorder

Bipolar Affective Psychosis

Bipolar Spectrum Disorder

Manic Depressive Illness

Depression Bipolar

Bipolar Disorder, Mixed

Major Affective Disorder

Major Affective Disorder 1

Major Affective Disorder 2

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Canis familiaris NCAN VGNC VGNC:43638
Rattus norvegicus NCAN RGD RGD:619941
Felis catus NCAN VGNC VGNC:82375
Bos taurus NCAN VGNC VGNC:31900
Mus musculus NCAN MGD MGI:104694
Others NCAN NCBI