GSG1L - GSG1 like Gene

Homo sapiens

Also known as PRO19651

Gene ID: 146395 | Gene type: protein coding

About GSG1L

Cytogenetic location: 16p12.1 Genomic coordinates (GRCh38): 16:27,787,528-28,063,714 (from NCBI)

This gene has 5 transcripts (splice variants), 232 orthologues and 10 paralogues. Biased expression in brain (RPKM 2.2), heart (RPKM 1.7) and 2 other tissues.

Summary

Predicted to be involved in regulation of AMPA Receptor activity. Predicted to be located in postsynaptic density. Predicted to be active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and plasma membrane. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

GSG1L Products(4)

mRNA	Protein	Name
NM_001109763.2	NP_001103233.1	germ cell-specific gene 1-like protein isoform 1 precursor
NM_001323900.2	NP_001310829.1	germ cell-specific gene 1-like protein isoform 3 precursor
NM_001323901.2	NP_001310830.1	germ cell-specific gene 1-like protein isoform 4 precursor
NM_144675.3	NP_653276.1	germ cell-specific gene 1-like protein isoform 2

GSG1L Protein Structure

GSG-1

0
100
200
300
331 a.a.

Protein Preferred Names

Protein Names

germ cell-specific gene 1-like protein

GSG1-like protein

GSG1L Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	GSG1L	Q6UXU4	LXN	Homo sapiens	Q9BS40	Y2H Prey Pooling	25416956
Intra	GSG1L	Q6UXU4	LXN	Homo sapiens	Q9BS40	Validated Y2H	25416956
Intra	GSG1L	Q6UXU4	LXN	Homo sapiens	Q9BS40	Y2H Array	25416956

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases

Alias

Arthrogryposis, Distal, Type 2a

Freeman-Sheldon Syndrome	Craniocarpotarsal Dystrophy
Craniocarpotarsal Dysplasia	DA2A
Whistling Face-Windmill Vane Hand Syndrome	Fss
Distal Arthrogryposis Type 2a	Whistling Face Syndrome
Freeman-Burian Syndrome	Arthrogryposis Distal Type 2a
Distal Arthrogryposis, Type 2a	Fbs
Arthrogryposis, Distal, 2a

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05861	GSG1L Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	GSG1L	VGNC	VGNC:80579
Bos taurus	GSG1L	VGNC	VGNC:29677
Canis familiaris	GSG1L	VGNC	VGNC:41529
Rattus norvegicus	GSG1L	RGD	RGD:1562278
Macaca mulatta	GSG1L	VGNC	VGNC:82152
Mus musculus	GSG1L	MGD	MGI:2685483

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