1. Gene
  2. BPIFB4 - BPI fold containing family B member 4 Gene

BPIFB4 - BPI fold containing family B member 4 Gene

Homo sapiens

Also known as RY2G5; LPLUNC4; C20orf186; dJ726C3.5

Gene ID: 149954 | Gene type: protein coding

About BPIFB4

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:33,079,643-33,111,751 (from NCBI)

This gene has 4 transcripts (splice variants), 106 orthologues and 12 paralogues. Low expression observed in reference dataset.

Summary

Predicted to enable lipid binding activity. Predicted to be located in cytoplasm and extracellular region. [provided by Alliance of Genome Resources, Apr 2022]

BPIFB4 Products(1)

mRNA Protein Name
NM_182519.3 NP_872325.2 BPI fold-containing family B member 4 precursor

BPIFB4 Protein Structure

LBP_BPI_CETP

LBP_BPI_CETP: LBP / BPI / CETP family, N-terminal domain (210 - 339)

LBP_BPI_CETP_C

LBP_BPI_CETP_C: LBP / BPI / CETP family, C-terminal domain (419 - 614)

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  • 614 a.a.
Protein Preferred Names Protein Names

BPI fold-containing family B member 4

ligand-binding protein RY2G5

Related Diseases

Diseases Alias
Midface Dysplasia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus BPIFB4 VGNC VGNC:50027
Macaca mulatta BPIFB4 VGNC VGNC:70321
Canis familiaris BPIFB4 VGNC VGNC:38510
Felis catus BPIFB4 VGNC VGNC:60158
Rattus norvegicus BPIFB4 RGD RGD:1561174
Mus musculus BPIFB4 MGD MGI:2685852