SLC9B1 - solute carrier family 9 member B1 Gene

Homo sapiens

Also known as NHA1; NHEDC1

Gene ID: 150159 | Gene type: protein coding

About SLC9B1

Cytogenetic location: 4q24 Genomic coordinates (GRCh38): 4:102,885,049-103,019,705 (from NCBI)

This gene has 11 transcripts (splice variants), 291 orthologues and 1 paralogue. Broad expression in testis (RPKM 16.0), kidney (RPKM 1.8) and 17 other tissues.

Summary

The protein encoded by this gene is a sodium/hydrogen exchanger and transmembrane protein. Highly conserved orthologs of this gene have been found in Other mammalian species. The expression of this gene may be limited to testis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

SLC9B1 Products(2)

mRNA	Protein	Name
NM_001100874.3	NP_001094344.2	sodium/hydrogen exchanger 9B1 isoform 2
NM_139173.4	NP_631912.3	sodium/hydrogen exchanger 9B1 isoform 1

SLC9B1 Protein Structure

Na_H_Exchanger

0
100
200
300
400
515 a.a.

Protein Preferred Names

Protein Names

sodium/hydrogen exchanger 9B1

NHE domain-containing protein 1

Related Diseases

Diseases

Alias

Wolfram Syndrome 2

WFS2

Tinea Nigra

Microsporosis Nigra	Infection By Cladosporium Werneckii
Keratomycosis Nigricans	Tinea Palmaris Nigra
Keratomycosis Nigricans Palmaris

Christianson Syndrome

X-Linked Angelman-Like Syndrome	X-Linked Intellectual Disability, South African Type
X-Linked Intellectual Disability-Craniofacial Dysmorphism-Epilepsy-Ophthalmoplegia-Cerebellar Atrophy Syndrome	Mental Retardation, Microcephaly, Epilepsy, And Ataxia Syndrome
Mental Retardation, X-Linked Syndromic, Christianson Type	Mrxsch
Angelman-Like Syndrome X-Linked	Intellectual Disability Microcephaly Epilepsy And Ataxia Syndrome
Intellectual Disability X-Linked Syndromic Christianson Type	Mrxs Christianson
X-Linked Intellectual Disability - Craniofacial Dysmorphism - Epilepsy - Ophthalmoplegia - Cerebellar Atrophy	Angelman-Like Syndrome, X-Linked
Intellectual Deficit, X-Linked, South African Type	Mental Retardation X-Linked, South African Type
Mental Retardation, X-Linked, Syndromic, Christianson Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13349	SLC9B1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SLC9B1	VGNC	VGNC:100270
Rattus norvegicus	SLC9B1	RGD	RGD:1305087
Mus musculus	SLC9B1	MGD	MGI:1921696
Canis familiaris	SLC9B1	VGNC	VGNC:57412

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