2. Gene
  3. Hadh - hydroxyacyl-Coenzyme A dehydrogenase Gene

Hadh - hydroxyacyl-Coenzyme A dehydrogenase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HCDH; Schad; Hadhsc

Gene ID: 15107 | Gene type: protein coding

About Hadh

Summary

Enables 3-hydroxyacyl-CoA dehydrogenase activity. Involved in positive regulation of cold-induced thermogenesis and regulation of Insulin secretion. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase). [provided by Alliance of Genome Resources, Apr 2022]

Hadh Products(1)

mRNA Protein Name
NM_008212.4 NP_032238.2 hydroxyacyl-coenzyme A dehydrogenase, mitochondrial precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables 3-hydroxyacyl-CoA dehydrogenase activity IDA
IDA: Inferred from direct assay
15240869 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20670938 MGI
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
21990309 MGI
involved in regulation of insulin secretion IMP
IMP: Inferred from mutant phenotype
20670938 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
26767982 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain

hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase

medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase

short-chain 3-hydroxyacyl-CoA dehydrogenase

Recombinant Hadh Proteins

Cat. No. Product Name Accession Purity
HY-P71563 HCDH Protein, Mouse (His-SUMO) Q61425 (S13-K314) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-E70239 2-Methylbutyryl-CoA / Unkown
HY-RS05989 HADH Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hadh NCBI NCBI:3033