2. Gene
  3. GPR155 - G protein-coupled receptor 155 Gene

GPR155 - G protein-coupled receptor 155 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DEP.7; PGR22; DEPDC3

Gene ID: 151556 | Gene type: protein coding

About GPR155

This gene has 6 transcripts (splice variants), 274 orthologues and 3 paralogues. Ubiquitous expression in stomach (RPKM 11.2), brain (RPKM 8.6) and 24 other tissues.

Summary

Involved in cognition. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

GPR155 Products(4)

mRNA Protein Name
NM_001033045.4 NP_001028217.1 integral membrane protein GPR155 isoform 1
NM_001267050.2 NP_001253979.1 integral membrane protein GPR155 isoform 1
NM_001267051.2 NP_001253980.1 integral membrane protein GPR155 isoform 2
NM_152529.7 NP_689742.4 integral membrane protein GPR155 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables cholesterol binding IDA
IDA: Inferred from direct assay
36007018 GOA
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to amino acid starvation IDA
IDA: Inferred from direct assay
36007018 GOA
involved in cellular response to cholesterol IDA
IDA: Inferred from direct assay
36007018 GOA
involved in cognition IMP
IMP: Inferred from mutant phenotype
17519220 GOA
involved in positive regulation of TORC1 signaling IDA
IDA: Inferred from direct assay
36007018 GOA
Cellular Component GO Annotation Evidence Reference Source
is active in lysosomal membrane IDA
IDA: Inferred from direct assay
36007018 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GPR155 Protein Structure

Mem_trans

Mem_trans: Membrane transport protein (45 - 189)

Mem_trans

Mem_trans: Membrane transport protein (204 - 360)

DEP

DEP: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) (767 - 833)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 870 a.a.
Protein Preferred Names Protein Names

integral membrane protein GPR155

G-protein coupled receptor PGR22

Related Diseases

Diseases Alias
Noonan Syndrome 13

NS13
Isolated Growth Hormone Deficiency, Type Ib

Isolated Growth Hormone Deficiency Type Ib

IGHD1B

Ighd Ib

Growth Hormone Deficiency, Isolated, Type Ib

Congenital Ighd Type Ib

Congenital Isolated Gh Deficiency Type Ib

Congenital Isolated Growth Hormone Deficiency Type Ib

Dwarfism Of Sindh

Pituitary Dwarfism I

Isolated Growth Hormone Deficiency Type 1b

Ighd 1b

Growth Hormone Deficiency, Isolated, 1b
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05672 GPR155 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta GPR155 VGNC VGNC:72985
Felis catus GPR155 VGNC VGNC:62680
Rattus norvegicus GPR155 RGD RGD:1309162
Bos taurus GPR155 VGNC VGNC:29561
Canis familiaris GPR155 VGNC VGNC:41407
Mus musculus GPR155 MGD MGI:1915776
Others GPR155 NCBI