CTSW - cathepsin W Gene

Homo sapiens

Also known as LYPN

Gene ID: 1521 | Gene type: protein coding

About CTSW

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:65,879,837-65,883,741 (from NCBI)

This gene has 8 transcripts (splice variants), 454 orthologues and 12 paralogues. Biased expression in bone marrow (RPKM 42.0), spleen (RPKM 24.6) and 12 other tissues.

Summary

The protein encoded by this gene, a member of the peptidase C1 family, is a cysteine proteinase that may have a specific function in the mechanism or regulation of T-cell cytolytic activity. The encoded protein is found associated with the membrane inside the endoplasmic reticulum of natural killer and cytotoxic T-cells. Expression of this gene is up-regulated by interleukin-2. [provided by RefSeq, Jul 2008]

CTSW Products(1)

mRNA	Protein	Name
NM_001335.4	NP_001326.3	cathepsin W preproprotein

CTSW Protein Structure

Inhibitor_I29

Peptidase_C1

0
100
200
300
376 a.a.

Protein Preferred Names

Protein Names

cathepsin W

lymphopain

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03348	CTSW Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CTSW	VGNC	VGNC:61272
Mus musculus	CTSW	MGD	MGI:1338045
Canis familiaris	CTSW	VGNC	VGNC:39716
Bos taurus	CTSW	VGNC	VGNC:27819
Macaca mulatta	CTSW	VGNC	VGNC:71563
Rattus norvegicus	CTSW	RGD	RGD:1309354
Others	CTSW	NCBI

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