CYP2D7 - cytochrome P450 family 2 subfamily D member 7 (gene/pseudogene) Gene

Homo sapiens

Also known as CYP2D; CYP2D6; CYP2D@; CYP2D7P; P450C2D; P450DB1; CYP2D7AP; CYP2D7P1; RNA40057

Gene ID: 1564 | Gene type: protein coding

About CYP2D7

Summary

This gene is a member of the Cytochrome P450 gene superfamily. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and Other lipids. This gene is a segregating pseudogene, where some individuals may have an allele that encodes a functional Enzyme, while Other individuals have an allele encoding a protein that is predicted to be non-functional. In this case, the functional allele is thought to be rare. This locus is part of a cluster of Cytochrome P450 genes on chromosome 22. [provided by RefSeq, Jan 2017]

CYP2D7 Products(1)

mRNA	Protein	Name
NM_001348386.3	NP_001335315.1	putative cytochrome P450 2D7

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
NOT enables aromatase activity	IDA IDA: Inferred from direct assay	18838503	GOA
enables aromatase activity	IDA IDA: Inferred from direct assay	15051713	GOA

Biological Process GO Annotation	Evidence	Reference	Source
NOT involved in xenobiotic catabolic process	IDA IDA: Inferred from direct assay	18838503	GOA
involved in xenobiotic catabolic process	IDA IDA: Inferred from direct assay	15051713	GOA
NOT involved in xenobiotic metabolic process	IDA IDA: Inferred from direct assay	18838503	GOA
involved in xenobiotic metabolic process	IDA IDA: Inferred from direct assay	15051713	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	15051713	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	18838503	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

putative cytochrome P450 2D7

Putative cytochrome P450 2D7

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03462	CYP2D7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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