USP51 - ubiquitin specific peptidase 51 Gene

Homo sapiens

Gene ID: 158880 | Gene type: protein coding

About USP51

This gene has 2 transcripts (splice variants), 46 orthologues and 71 paralogues. Broad expression in thyroid (RPKM 4.9), ovary (RPKM 3.8) and 23 other tissues.

Summary

Enables chromatin binding activity; histone binding activity; and thiol-dependent Deubiquitinase. Involved in histone deubiquitination; regulation of cell cycle process; and regulation of double-strand break repair. Predicted to be located in chromosome. [provided by Alliance of Genome Resources, Apr 2022]

USP51 Products(1)

mRNA	Protein	Name
NM_201286.4	NP_958443.1	ubiquitin carboxyl-terminal hydrolase 51

USP51 Protein Structure

zf-UBP

UCH

0
200
400
600
711 a.a.

Protein Preferred Names

Protein Names

ubiquitin carboxyl-terminal hydrolase 51

deubiquitinating enzyme 51

Related Diseases

Diseases

Alias

Non-Syndromic X-Linked Intellectual Disability 99

Mrx99

X-Linked Mental Retardation 99

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15563	USP51 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	USP51	MGD	MGI:3588217
Rattus norvegicus	USP51	RGD	RGD:1562211
Others	USP51	NCBI

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