1. Gene
  2. CLEC4C - C-type lectin domain family 4 member C Gene

CLEC4C - C-type lectin domain family 4 member C Gene

Homo sapiens

Also known as DLEC; HECL; BDCA2; CD303; BDCA-2; CLECSF7; CLECSF11; PRO34150

Gene ID: 170482 | Gene type: protein coding

About CLEC4C

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:7,729,383-7,749,541 (from NCBI)

This gene has 6 transcripts (splice variants), 747 orthologues and 14 paralogues. Biased expression in lymph node (RPKM 1.5), spleen (RPKM 0.9) and 6 other tissues.

Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

CLEC4C Products(4)

mRNA Protein Name
NM_001371390.1 NP_001358319.1 C-type lectin domain family 4 member C isoform 1
NM_001371391.1 NP_001358320.1 C-type lectin domain family 4 member C isoform 3
NM_130441.3 NP_569708.1 C-type lectin domain family 4 member C isoform 1
NM_203503.2 NP_987099.1 C-type lectin domain family 4 member C isoform 2

CLEC4C Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (102 - 208)

  • 0
  • 100
  • 200
  • 213 a.a.
Protein Preferred Names Protein Names

C-type lectin domain family 4 member C

C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 11

Recombinant CLEC4C Proteins

Cat. No. Product Name Accession Purity
HY-P71679 CLEC4C Protein, Human (HEK293, His, Myc) Q8WTT0-1 (N45-I213) ≥95%
HY-P72014 CLEC4C Protein, Human (His-SUMO) Q8WTT0-1 (N45-I213) ≥95%
HY-P78387 CLEC4C Protein, Human (Biotinylated, HEK293, His-Avi) Q8WTT0-1 (F46-I213) ≥95%

Related Diseases

Diseases Alias
Cutaneous Lupus Erythematosus

Lupus Erythematosus, Cutaneous

Lupus Erythematosus Cutaneous

Cardiomyopathy, Dilated, 1c, With Or Without Left Ventricular Noncompaction

Left Ventricular Noncompaction 3

Dilated Cardiomyopathy 1c

CMD1C

Cardiomyopathy, Hypertrophic, 24

Dilated Cardiomyopathy With Left Ventricular Noncompaction

Cardiomyopathy, Dilated, 1c, With Or Without Lvnc

Cmdc1

Dilated Cardiomyopathy 1c With Or Without Left Ventricular Noncompaction

Cardiomyopathy, Dilated 1c, With Or Without Left Ventricular Non-Compaction

Cardiomyopathy Dilated With Left Ventricular Noncompaction

Cardiomyopathy, Familial Hypertrophic 24

CMH24

Left Ventricular Non-Compaction 3

LVNC3

Cardiomyopathy, Dilated 1c

Familial Hypertrophic Cardiomyopathy 24

Cardiomyopathy, Dilated, 1c

Inflammatory Bowel Disease 23

IBD23

Pitt-Hopkins Syndrome

PTHS

Encephalopathy, Severe Epileptic, With Autonomic Dysfunction

Mental Retardation, Syndromal, With Intermittent Hyperventilation

Intellectual Disability, Wide Mouth, Distinctive Facial Features, And Intermittent Hyperventilation Followed By Apnea

Pitt Hopkins Syndrome

Phs

Encephalopathy Severe Epileptic With Autonomic Dysfunction

Systemic Lupus Erythematosus

Lupus Nephritis

SLE

Disseminated Lupus Erythematosus

Systemic Lupus Erythematosus, Susceptibility To

Lupus Erythematosus, Systemic

Lupus Nephritis, Susceptibility To

Libman-Sacks Disease

Systemic Lupus Erythematosus Susceptibility To

Sle - Lupus Erythematosus, Systemic

Le Syndrome

Lupus

Lupus Erythematosus Systemic

Lupus Erythematosus, Systemic, Susceptibility To

Lupus Vulgaris

Lupus Erythematosus, Discoid

Lupus Erythematosus

Systemic Lupus Erythematosus Nos

Sle - [Systemic Lupus Erythematosus]

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Mus musculus CLEC4C MGD MGI:1917060
Rattus norvegicus CLEC4C RGD RGD:1359354
Macaca mulatta CLEC4C VGNC VGNC:99915
Macaca fascicularis CLEC4C NCBI NCBI:102147129
Others CLEC4C NCBI