Hrh4 - histamine receptor H4 Gene

Rattus norvegicus

Gene ID: 170704 | Gene type: protein coding

About Hrh4

Primary_assembly 18: 4,166,270-4,246,345 forward strand.mRatBN7.2:CM026991.1

This gene has 1 transcript (splice variant), 105 orthologues, 35 paralogues and is associated with 4 phenotypes. Biased expression in Testes (RPKM 1.2), Thymus (RPKM 1.1) and 1 other tissue.

Summary

Enables Histamine Receptor activity. Involved in inflammatory response. Predicted to be located in membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Orthologous to human HRH4 (Histamine Receptor H4). [provided by Alliance of Genome Resources, Apr 2022]

Hrh4 Products(1)

mRNA	Protein	Name
NM_131909.2	NP_571984.2	histamine H4 receptor

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables histamine receptor activity	IDA IDA: Inferred from direct assay	11561071	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Hrh4 Protein Structure

7tm_GPCRs

0
100
200
300
391 a.a.

Protein Preferred Names

Protein Names

histamine H4 receptor

H4R

HH4R

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06368	HRH4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06369	Hrh4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS06370	Hrh4 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Hrh4	NCBI	NCBI:59340

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