2. Gene
  3. Il1rl1 - interleukin 1 receptor-like 1 Gene

Il1rl1 - interleukin 1 receptor-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as T1; St2; DER4; Ly84; ST2L; Fit-1; T1/ST2; St2-rs1

Gene ID: 17082 | Gene type: protein coding

About Il1rl1

Summary

Enables interleukin-33 binding activity and interleukin-33 receptor activity. Involved in several processes, including negative regulation of T-helper 1 type immune response; positive regulation of macrophage activation; and regulation of cytokine production. Acts upstream of or within negative regulation of I-kappaB kinase/NF-kappaB signaling. Located in external side of plasma membrane and extracellular matrix. Is expressed in several structures, including immune system; musculoskeletal system; salivary gland; skin; and visual system. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1). [provided by Alliance of Genome Resources, Apr 2022]

Il1rl1 Products(3)

mRNA Protein Name
NM_001025602.3 NP_001020773.1 interleukin-1 receptor-like 1 isoform a precursor
NM_001294171.1 NP_001281100.1 interleukin-1 receptor-like 1 isoform b precursor
NM_010743.3 NP_034873.2 interleukin-1 receptor-like 1 isoform b precursor
Protein Preferred Names Protein Names

interleukin-1 receptor-like 1

interleukin-33 receptor alpha chain

lymphocyte antigen 84

Recombinant Il1rl1 Proteins

Cat. No. Product Name Accession Purity
HY-P72459 ST2/IL1RL1 Protein, Mouse (HEK293, His) P14719-2 (S27-A337) ≥95%
HY-P76661 ST2/IL1RL1 Protein, Mouse (332a.a, HEK293, Fc) P14719 (M1-R332) ≥95%
HY-P76662 ST2/IL1RL1 Protein, Mouse (332a.a, HEK293, His) P14719 (M1-R332) ≥95%

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99729 Melrilimab Inhibitor 96.07% Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06725 IL1RL1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1rl1 NCBI NCBI:9173
Macaca fascicularis Il1rl1 NCBI NCBI:102115135