1. Gene
  2. Maf - avian musculoaponeurotic fibrosarcoma oncogene homolog Gene

Maf - avian musculoaponeurotic fibrosarcoma oncogene homolog Gene

Mus musculus

Also known as c-maf; 2810401A20Rik; A230108G15Rik

Gene ID: 17132 | Gene type: protein coding

About Maf

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Acts upstream of or within several processes, including regulation of chondrocyte differentiation; regulation of transcription by RNA polymerase II; and sensory organ development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and lower leg. Used to study cataract 21 multiple types and multiple myeloma. Human ortholog(s) of this gene implicated in Ayme-Gripp syndrome; cataract; and cataract 21 multiple types. Orthologous to human MAF (MAF bZIP transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Maf Products(1)

mRNA Protein Name
NM_001025577.2 NP_001020748.2 transcription factor Maf
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables DNA binding IDA
IDA: Inferred from direct assay
12381733 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
19414009 MGI
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
12835653 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12381733 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10603348 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15249232 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15249232 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor Maf

V-maf musculoaponeurotic fibrosarcoma oncogene homolog

avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog

c-Maf long form

proto-oncogene c-maf

Orthologs Information

Species Symbol Source ID
Homo sapiens Maf NCBI NCBI:4094
Macaca fascicularis Maf NCBI NCBI:102120730