2. Gene
  3. Cma1 - chymase 1, mast cell Gene

Cma1 - chymase 1, mast cell Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Mcp5; Mcp-5; Mcpt5; MMCP-5

Gene ID: 17228 | Gene type: protein coding

About Cma1

Summary

This gene encodes a serine protease that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive Peptides. The encoded preproprotein undergoes proteolytic processing to generate a functional Enzyme with elastase-like activity. Mice lacking the encoded protein exhibit significant attenuation of ischemia-reperfusion injury of the skeletal muscle. This gene is located in a cluster of related mast cell protease genes on chromosome 14. [provided by RefSeq, Nov 2015]

Cma1 Products(1)

mRNA Protein Name
NM_010780.3 NP_034910.2 chymase preproprotein
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
9360993 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

chymase

alpha-chymase

mast cell chymase 1

mast cell protease 5

mast cell protease I

Recombinant Cma1 Proteins

Cat. No. Product Name Accession Purity
HY-P72290 Chymase/CMA1 Protein, Mouse (His) P21844 (I22-E246) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02853 CMA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cma1 NCBI NCBI:1215