2. Gene
  3. Mmp7 - matrix metallopeptidase 7 Gene

Mmp7 - matrix metallopeptidase 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MAT; MMP-7

Gene ID: 17393 | Gene type: protein coding

About Mmp7

Chromosome 9: 7,692,091-7,699,586 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 163 orthologues, 23 paralogues and is associated with 18 phenotypes. Biased expression in large intestine adult (RPKM 146.), small intestine adult (RPKM 25.5) and 2 other tissues.

Summary

This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading Enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase Enzyme. Mice lacking the encoded protein are deficient in functional cryptdins. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016]

Mmp7 Products(2)

mRNA Protein Name
NM_010810.5 NP_034940.2 matrilysin isoform 1 preproprotein
NM_001319986.1 NP_001306915.1 matrilysin isoform 2

Mmp7 Protein Structure

PG_binding_1

PG_binding_1: pfam01471 (33 - 84)

Peptidase_M10

Peptidase_M10: pfam00413 (105 - 261)

  • 0
  • 100
  • 200
  • 267 a.a.
Protein Preferred Names Protein Names

matrilysin

matrilysin, uterine

matrin

matrix metalloproteinase 7

pump-1 protease

uterine metalloproteinase

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-12169 Marimastat Inhibitor ≥98.0% Phase 3
Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13564 Batimastat Inhibitor 98.92% Unkown
HY-103444 ARP-100 Inhibitor ≥99.0% Unkown
HY-N0774 Isofraxidin Inhibitor 99.00% Unkown
HY-151540 MMP-7-IN-1 Inhibitor 99.68% Unkown
HY-131498 MOCAc-PLGL(Dpa)AR 99.86% Unkown
HY-156430 MMP-7-IN-3 Inhibitor 99.93% Unkown
HY-RS08552 Mmp7 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-153563 MMP-7-IN-2 Inhibitor 99.34% Unkown
HY-119423 MMP Inhibitor II Inhibitor / Unkown
HY-161169 TP0628103 Inhibitor / Unkown
HY-130076 MMP-2 Inhibitor II Inhibitor / Unkown
HY-RS08551 MMP7 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS08553 Mmp7 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-13564A Batimastat sodium salt Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mmp7 NCBI NCBI:4316