DMWD - DM1 locus, WD repeat containing Gene

Homo sapiens

Also known as DMRN9; DMR-N9; gene59; D19S593E

Gene ID: 1762 | Gene type: protein coding

About DMWD

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:45,782,947-45,792,845 (from NCBI)

This gene has 8 transcripts (splice variants), 186 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 11.5), brain (RPKM 11.3) and 25 other tissues.

Summary

Predicted to be located in dendrite; nucleus; and perikaryon. [provided by Alliance of Genome Resources, Apr 2022]

DMWD Products(1)

mRNA	Protein	Name
NM_004943.2	NP_004934.1	dystrophia myotonica WD repeat-containing protein

Gene Ontology

Molecular Function
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables deubiquitinase activator activity	IDA IDA: Inferred from direct assay	33844468	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	33844468	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
located in cytoplasm	IDA IDA: Inferred from direct assay	33844468	GOA
located in nucleus	IDA IDA: Inferred from direct assay	33844468	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DMWD Protein Structure

WD40

0
200
400
600
674 a.a.

Protein Preferred Names

Protein Names

dystrophia myotonica WD repeat-containing protein

dystrophia myotonica, WD repeat containing

Related Diseases

Diseases

Alias

Myotonic Dystrophy 1

Myotonic Dystrophy	Dystrophia Myotonica
Steinert Disease	Myotonic Dystrophy Type 1
Myotonia Atrophica	DM1
Congenital Myotonic Dystrophy	Myotonia Dystrophica
Steinert Myotonic Dystrophy	Dystrophia Myotonica 1
Dm	Steinert'S Disease
Steinert Myotonic Dystrophy Syndrome	Myotonic Dystrophy Of Steinert
Dystrophia Myotonica Type 1	Myotonic Dystrophy Congenital
Dystrophy, Myotonic, Type 1	Dm - [Dystrophia Myotonica]
Myotonic Muscular Dystrophy

Corticosteroid Allergy

Suppurative Cholangitis

Arthrogryposis, Distal, Type 1a

Distal Arthrogryposis Type 1	Digitotalar Dysmorphism
DA1A	Da1
Amcd1	Arthrogryposis, Distal, Type 2b4
Distal Arthrogryposis Type 1a	Arthrogryposis, Distal, Type 1
Arthrogryposis Multiplex Congenita Distal Type 1	Arthrogryposis Multiplex Congenita, Distal Type 1
Arthrogryposis Multiplex Congenita, Distal, Type I	Distal Arthrogryposis Type 1b
Arthrogryposis, Distal, 1a	Amc
Arthrogryposis Multiplex Congenita	Arthrogryposis, Distal, 2b4
DA2B4	Arthrogryposis Multiplex Congenita, Distal, Type 1
Arthrogryposis

Hermansky-Pudlak Syndrome 7

HPS7	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial
Delta Storage Pool Disease	Hermansky-Pudlak Syndrome, Type 7
Platelet Storage Pool Deficiency	Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03835	DMWD Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	DMWD	RGD	RGD:1594179
Bos taurus	DMWD	VGNC	VGNC:97261
Mus musculus	DMWD	MGD	MGI:94907

Name
Email *

	Sorry, but the email address you supplied was invalid.