Nid1 - nidogen 1 Gene

Mus musculus

Also known as Nid; entactin; nidogen-1; A630025O17; entactin-1

Gene ID: 18073 | Gene type: protein coding

About Nid1

Summary

Enables collagen binding activity and laminin-1 binding activity. Acts upstream of or within cell-matrix adhesion; glomerular basement membrane development; and positive regulation of cell-substrate adhesion. Located in basement membrane. Is expressed in several structures, including alimentary system; blastocyst; eye; genitourinary system; and nervous system. Orthologous to human NID1 (nidogen 1). [provided by Alliance of Genome Resources, Apr 2022]

Nid1 Products(1)

mRNA	Protein	Name
NM_010917.3	NP_035047.2	nidogen-1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables collagen binding	IDA IDA: Inferred from direct assay	17517882	MGI
enables extracellular matrix binding	IDA IDA: Inferred from direct assay	18757743	MGI
enables laminin-1 binding	IDA IDA: Inferred from direct assay	17517882	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	8995276	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within cell-matrix adhesion	IDA IDA: Inferred from direct assay	12243745	MGI
acts upstream of or within extracellular matrix organization	IDA IDA: Inferred from direct assay	18757743	MGI
acts upstream of or within glomerular basement membrane development	IMP IMP: Inferred from mutant phenotype	14566019	MGI
acts upstream of or within positive regulation of cell-substrate adhesion	IDA IDA: Inferred from direct assay	18757743	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in basement membrane	IDA IDA: Inferred from direct assay	7670489	MGI
located in basement membrane	IPI IPI: Inferred from physical interaction	12243745	MGI
located in cell periphery	IDA IDA: Inferred from direct assay	19295126	MGI
located in extracellular matrix	IDA IDA: Inferred from direct assay	16618944	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

nidogen-1

NID-1	Nidogen precursor (Entactin)
entactin 1

Nid1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Nid1	P10493	Lamc1	Mus musculus	P02468	DLS	23948589

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Nid1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71763	Nidogen-1 Protein, Mouse (P.pastoris, His)	P10493 (428S-665A)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09294	NID1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nid1	NCBI	NCBI:4811

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