Ntsr1 - neurotensin receptor 1 Gene

Mus musculus

Also known as NTR1; NT-1R; NTR-1

Gene ID: 18216 | Gene type: protein coding

About Ntsr1

Chromosome 2: 180,141,769-180,186,773 forward strand.GRCm39:CM000995.3

This gene has 2 transcripts (splice variants), 213 orthologues, 14 paralogues and is associated with 16 phenotypes. Biased expression in CNS E18 (RPKM 4.6), genital fat pad adult (RPKM 1.5) and 1 other tissues.

Summary

Predicted to enable G protein-coupled Neurotensin Receptor activity; identical protein binding activity; and protein N-terminus binding activity. Acts upstream of or within adult locomotory behavior. Predicted to be located in several cellular components, including dendrite; perikaryon; and symmetric synapse. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; eye; gallbladder; intestine; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human NTSR1 (Neurotensin Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Ntsr1 Products(1)

mRNA	Protein	Name
NM_018766.2	NP_061236.1	neurotensin receptor type 1

Ntsr1 Protein Structure

7tmA_NTSR1

0
100
200
300
400
424 a.a.

Protein Preferred Names

Protein Names

neurotensin receptor type 1

NT-R-1

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-125880	SBI-553	Modulator	99.86%	Unkown
HY-RS09638	NTSR1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09639	Ntsr1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS09640	Ntsr1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ntsr1	NCBI	NCBI:4923
Macaca fascicularis	Ntsr1	NCBI	NCBI:102115340

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