2. Gene
  3. EPYC - epiphycan Gene

EPYC - epiphycan Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as PGLB; DSPG3; Pg-Lb; SLRR3B

Gene ID: 1833 | Gene type: protein coding

About EPYC

Cytogenetic location: 12q21.33 Genomic coordinates (GRCh38): 12:90,963,682-91,004,972 (from NCBI)

This gene has 3 transcripts (splice variants), 203 orthologues and 10 paralogues. Biased expression in placenta (RPKM 4.1), endometrium (RPKM 0.8) and 1 other tissue.

Summary

Dermatan sulfate proteoglycan 3 is a member of the small leucine-rich repeat proteoglycan family. This gene is composed of seven exons. It regulates fibrillogenesis by interacting with collagen fibrils and Other extracellular matrix proteins. [provided by RefSeq, Jul 2008]

EPYC Products(1)

mRNA Protein Name
NM_004950.5 NP_004941.2 epiphycan precursor

EPYC Protein Structure

LRRNT

LRRNT: Leucine rich repeat N-terminal domain (121 - 142)

LRR_8

LRR_8: Leucine rich repeat (152 - 203)

LRR_6

LRR_6: Leucine Rich repeat (211 - 229)

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  • 322 a.a.
Protein Preferred Names Protein Names

epiphycan

dermatan sulfate proteoglycan 3

Recombinant EPYC Proteins

Cat. No. Product Name Accession Purity
HY-P76323 DSPG3/Epiphycan Protein, Human (HEK293, His) Q99645 (A20-V322) ≥95%

Related Diseases

Diseases Alias
Corneal Dystrophy, Posterior Amorphous

Posterior Amorphous Corneal Dystrophy

PACD

Chromosome 12q21.33 Deletion Syndrome

Posterior Amorphous Stromal Dystrophy
Cornea Plana

Flat Cornea
Breast Apocrine Carcinoma

Apocrine Carcinoma Of Breast

Apocrine Breast Carcinoma
Stromal Dystrophy
Myopia

Near-Sightedness

Short-Sightedness

Nearsightedness

Nearsighted

Near Vision

Close Sighted

Myopic

Short-Sighted

Near Sighted
Corneal Dystrophy, Congenital Stromal

Congenital Stromal Corneal Dystrophy

CSCD

Congenital Hereditary Stromal Dystrophy

Congenital Hereditary Stromal Dystrophy Of The Cornea

Congenital Stromal Dystrophy Of The Cornea

Dacs

Decorin-Associated Congenital Stromal Corneal Dystrophy

Dystrophia Corneae Parenchymatosa Congenita

Witschel Dystrophy

Dystrophy, Corneal, Stromal, Congenital
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04460 EPYC Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EPYC RGD RGD:1305904
Canis familiaris EPYC VGNC VGNC:40431
Bos taurus EPYC VGNC VGNC:28558
Felis catus EPYC VGNC VGNC:61924
Mus musculus EPYC MGD MGI:107942
Macaca mulatta EPYC VGNC VGNC:72145
Others EPYC NCBI