2. Gene
  3. Pcolce - procollagen C-endopeptidase enhancer protein Gene

Pcolce - procollagen C-endopeptidase enhancer protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P14; Astt2; Astt-2; PCPE-1

Gene ID: 18542 | Gene type: protein coding

About Pcolce

Chromosome 5: 137,603,365-137,612,046 reverse strand.GRCm39:CM000998.3

This gene has 12 transcripts (splice variants), 246 orthologues, 35 paralogues and is associated with 9 phenotypes. Biased expression in adrenal adult (RPKM 519.4), ovary adult (RPKM 131.5) and 9 other tissues.

Summary

Predicted to enable collagen binding activity; heparin binding activity; and peptidase activator activity. Acts upstream of or within cellular response to Leukemia Inhibitory Factor and proteolysis. Located in extracellular space. Is expressed in several structures, including adrenal gland; branchial arch; embryo endoderm; lower jaw; and umbilical blood vessel. Orthologous to human PCOLCE (procollagen C-endopeptidase enhancer). [provided by Alliance of Genome Resources, Apr 2022]

Pcolce Products(1)

mRNA Protein Name
NM_008788.2 NP_032814.2 procollagen C-endopeptidase enhancer 1 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
26220971 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: Inferred from expression pattern
20439489 MGI
acts upstream of or within proteolysis IDA
IDA: Inferred from direct assay
7523404 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Pcolce Protein Structure

CUB

CUB: cd00041 (35 - 145)

CUB

CUB: cd00041 (157 - 270)

NTR_PCOLCE

NTR_PCOLCE: cd03576 (333 - 459)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 468 a.a.
Protein Preferred Names Protein Names

procollagen C-endopeptidase enhancer 1

astroglial cell transcript 2

procollagen C-proteinase enhancer 1

procollagen C-proteinase enhancer protein

procollagen COOH-terminal proteinase enhancer 1

type 1 procollagen C-proteinase enhancer protein

type I procollagen COOH-terminal proteinase enhancer

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10163 PCOLCE Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10164 Pcolce Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10165 Pcolce Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS10166 PCOLCE2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pcolce NCBI NCBI:5118