2. Gene
  3. Prss8 - serine protease 8 Gene

Prss8 - serine protease 8 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CAP1

Gene ID: 192107 | Gene type: protein coding

About Prss8

Summary

Predicted to enable Sodium Channel regulator activity. Involved in several processes, including positive regulation of sodium ion transmembrane transport; response to mineralocorticoid; and response to peptide hormone. Located in extracellular space. Used to study alopecia. Orthologous to human PRSS8 (serine protease 8). [provided by Alliance of Genome Resources, Apr 2022]

Prss8 Products(1)

mRNA Protein Name
NM_138836.1 NP_620191.1 prostasin precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of sodium ion transmembrane transport IDA
IDA: Inferred from direct assay
11373334 RGD
involved in response to mineralocorticoid IEP
IEP: Inferred from expression pattern
17468916 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
16528252 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12506133 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
12506133 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostasin

channel-activating protease 1

protease, serine, 8

Recombinant Prss8 Proteins

Cat. No. Product Name Accession Purity
HY-P77155 Prostasin/PRSS8 Protein, Rat (HEK293, His) Q9ES87 (A30-R322) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11259 PRSS8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prss8 NCBI NCBI:5652
Mus musculus Prss8 NCBI NCBI:76560