Ptgfr - prostaglandin F receptor Gene

Mus musculus

Also known as fp; PGF

Gene ID: 19220 | Gene type: protein coding

About Ptgfr

Chromosome 3: 151,502,139-151,543,267 reverse strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 195 orthologues, 7 paralogues and is associated with 3 phenotypes. Biased expression in ovary adult (RPKM 14.), heart adult (RPKM 2.7) and 5 other tissues.

Summary

Predicted to enable prostaglandin F receptor activity. Involved in positive regulation of gene expression and response to estradiol. Acts upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in cloaca; genital tubercle; jaw; and viscerocranium. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgfr Products(1)

mRNA	Protein	Name
NM_008966.3	NP_032992.1	prostaglandin F2-alpha receptor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	12606450	MGI
involved in positive regulation of gene expression	IDA IDA: Inferred from direct assay	21668646	MGI
involved in response to estradiol	IDA IDA: Inferred from direct assay	10684792	MGI
acts upstream of or within response to lipopolysaccharide	IMP IMP: Inferred from mutant phenotype	15834430	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ptgfr Protein Structure

7tmA_FP

0
100
200
300
366 a.a.

Protein Preferred Names

Protein Names

prostaglandin F2-alpha receptor

PGF receptor	PGF2-alpha receptor
prostaglandin F2alpha receptor	prostanoid FP receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11382	PTGFR Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11383	Ptgfr Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS11384	Ptgfr Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ptgfr	NCBI	NCBI:5737
Macaca fascicularis	Ptgfr	NCBI	NCBI:102139926

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