2. Gene
  3. Rb1 - RB transcriptional corepressor 1 Gene

Rb1 - RB transcriptional corepressor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Rb; pRb; Rb-1; pp105; p110-RB1

Gene ID: 19645 | Gene type: protein coding

About Rb1

Summary

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and Enzyme binding activity. Involved in several processes, including negative regulation of cold-induced thermogenesis; negative regulation of myofibroblast differentiation; and negative regulation of transcription involved in G1/S transition of mitotic cell cycle. Acts upstream of or within several processes, including hepatocyte apoptotic process; neuron development; and regulation of transcription by RNA polymerase II. Located in nucleus and spindle. Part of Rb-E2F complex. Is expressed in several structures, including alimentary system; central nervous system; hemolymphoid system; retina; and vibrissa. Human ortholog(s) of this gene implicated in nervous system Cancer (multiple); osteosarcoma; prostate cancer; small cell carcinoma; and urinary bladder Cancer. Orthologous to human RB1 (RB transcriptional corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Rb1 Products(1)

mRNA Protein Name
NM_009029.3 NP_033055.2 retinoblastoma-associated protein
Protein Preferred Names Protein Names

retinoblastoma-associated protein

retinoblastoma 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0039 Ginsenoside Rb1 98.75% Unkown
HY-N0904 Ginsenoside C-K Inhibitor 99.92% Unkown
HY-125848 Ginsenoside F2 Inducer 99.95% Unkown
HY-124962 D-NMAPPD 99.74% Unkown
HY-N7678 Gypenoside LXXV 98.80% Unkown
HY-RS11713 RB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-N0039R Ginsenoside Rb1 (Standard) / Unkown
HY-N0904R Ginsenoside C-K (Standard) Inhibitor / Unkown
HY-RS06683 IL12RB1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11714 RB1CC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-N8030 Pseudoginsenoside Rg3 / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990776 Vimekofusp / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rb1 NCBI NCBI:5925
Canis familiaris Rb1 NCBI NCBI:476915
Macaca fascicularis Rb1 NCBI NCBI:102145859
Rattus norvegicus Rb1 NCBI NCBI:24708
Macaca mulatta Rb1 NCBI NCBI:704871