2. Gene
  3. Rgs4 - regulator of G-protein signaling 4 Gene

Rgs4 - regulator of G-protein signaling 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ESTM48; ESTM50

Gene ID: 19736 | Gene type: protein coding

About Rgs4

Chromosome 1: 169,569,046-169,575,211 reverse strand.GRCm39:CM000994.3

This gene has 3 transcripts (splice variants), 197 orthologues, 23 paralogues and is associated with 32 phenotypes. Biased expression in cortex adult (RPKM 95.1), frontal lobe adult (RPKM 57.2) and 4 other tissues.

Summary

Predicted to enable G-protein alpha-subunit binding activity and GTPase activator activity. Predicted to be involved in several processes, including negative regulation of cell growth involved in cardiac muscle cell development; regulation of ion transport; and regulation of signal transduction. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be part of protein-containing complex. Is expressed in several structures, including eye; genitourinary system; gut; immune system; and nervous system. Orthologous to human RGS4 (regulator of G protein signaling 4). [provided by Alliance of Genome Resources, Apr 2022]

Rgs4 Products(1)

mRNA Protein Name
NM_009062.3 NP_033088.2 regulator of G-protein signaling 4

Rgs4 Protein Structure

RGS_RGS4

RGS_RGS4: cd08714 (62 - 175)

  • 0
  • 100
  • 205 a.a.
Protein Preferred Names Protein Names

regulator of G-protein signaling 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13509 CCG-50014 Inhibitor 99.42% Unkown
HY-U00431 CCG 203769 Inhibitor 99.76% Unkown
HY-70074 CCG-63802 Inhibitor 98.83% Unkown
HY-110054 CCG-2046 Inhibitor / Unkown
HY-122251 CCG-4986 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rgs4 NCBI NCBI:5999