2. Gene
  3. S100a8 - S100 calcium binding protein A8 (calgranulin A) Gene

S100a8 - S100 calcium binding protein A8 (calgranulin A) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p8; B8Ag; CFAg; Caga; MRP8; CP-10; 60B8Ag

Gene ID: 20201 | Gene type: protein coding

About S100a8

Summary

Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Acts upstream of or within astrocyte development and positive regulation of peptide secretion. Predicted to be located in cytosol and intermediate filament Cytoskeleton. Predicted to be active in extracellular space. Is expressed in several structures, including bone marrow; extraembryonic component; female reproductive system; and liver. Human ortholog(s) of this gene implicated in myocarditis. Orthologous to human S100A8 (S100 calcium binding protein A8). [provided by Alliance of Genome Resources, Apr 2022]

S100a8 Products(1)

mRNA Protein Name
NM_013650.2 NP_038678.1 protein S100-A8
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within astrocyte development IGI
IGI: Inferred from genetic interaction
22577135 MGI
acts upstream of peptide secretion IDA
IDA: Inferred from direct assay
18820689 MGI
acts upstream of peptide secretion IMP
IMP: Inferred from mutant phenotype
18820689 MGI
acts upstream of or within positive regulation of peptide secretion IDA
IDA: Inferred from direct assay
18820689 MGI
acts upstream of or within positive regulation of peptide secretion IMP
IMP: Inferred from mutant phenotype
18820689 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein S100-A8

MRP-8

S100 calcium-binding protein A8

calgranulin-A

chemotactic S100 protein

chemotactic cytokine CP-10

leukocyte L1 complex light chain

migration inhibitory factor-related protein 8

pro-inflammatory S100 cytokine

Recombinant S100a8 Proteins

Cat. No. Product Name Accession Purity
HY-P71779 S100A8 Protein, Mouse (P.pastoris, His) P27005 (2P-89E) ≥95%
HY-P73671 S100A8 Protein, Mouse (sf9, His) P27005 (M1-E89) ≥95%

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-100442 Paquinimod Inhibitor 99.90% Phase 2
Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-141537 ABR-238901 Inhibitor 98.71% Unkown
HY-100442S1 Paquinimod-d5-1 Inhibitor 98.19% Unkown
HY-RS12385 S100A8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-100442S Paquinimod-d5 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S100a8 NCBI NCBI:6279
Rattus norvegicus S100a8 NCBI NCBI:116547