1. Gene
  2. Slc2a2 - solute carrier family 2 (facilitated glucose transporter), member 2 Gene

Slc2a2 - solute carrier family 2 (facilitated glucose transporter), member 2 Gene

Mus musculus

Also known as Glut2; Glut-2

Gene ID: 20526 | Gene type: protein coding

About Slc2a2

Chromosome 3: 28,752,052-28,785,508 forward strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 312 orthologues, 11 paralogues and is associated with 20 phenotypes. Biased expression in liver adult (RPKM 5.7), liver E18 (RPKM 37.6) and 7 other tissues.

Summary

Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Located in several cellular components, including apical plasma membrane; brush border; and cell-cell junction. Is expressed in several structures, including alimentary system; early conceptus; liver; metanephros; and testis. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Fanconi syndrome; glycogen storage disease; and type 2 diabetes mellitus. Orthologous to human SLC2A2 (solute carrier family 2 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a2 Products(1)

mRNA Protein Name
NM_031197.2 NP_112474.2 solute carrier family 2, facilitated glucose transporter member 2

Slc2a2 Protein Structure

MFS_GLUT_Class1

MFS_GLUT_Class1: cd17431 (11 - 488)

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  • 523 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 2

glucose transporter type 2, liver

liver-type glucose transporter

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a2 NCBI NCBI:6514