2. Gene
  3. Serpini1 - serine (or cysteine) peptidase inhibitor, clade I, member 1 Gene

Serpini1 - serine (or cysteine) peptidase inhibitor, clade I, member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ns; PI12; PI-12; Spi17

Gene ID: 20713 | Gene type: protein coding

About Serpini1

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity; positive regulation of neuron projection development; and regulation of cell adhesion. Predicted to act upstream of or within negative regulation of peptidase activity. Located in neuronal cell body and secretory granule lumen. Is expressed in several structures, including early conceptus; enteric nervous system; intestine; retina; and secondary oocyte. Used to study familial encephalopathy with neuroserpin inclusion bodies. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]

Serpini1 Products(2)

mRNA Protein Name
NM_001357514.1 NP_001344443.1 neuroserpin isoform 2 precursor
NM_009250.3 NP_033276.1 neuroserpin isoform 1 precursor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in neuronal cell body IDA
IDA: Inferred from direct assay
17040209 MGI
located in secretory granule lumen IDA
IDA: Inferred from direct assay
17040209 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuroserpin

peptidase inhibitor 12

protease inhibitor 17

serine protease inhibitor 17

serpin I1

Recombinant Serpini1 Proteins

Cat. No. Product Name Accession Purity
HY-P74703 Neuroserpin Protein, Mouse (HEK293, His) O35684 (T17-L410) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12729 SERPINI1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpini1 NCBI NCBI:5274