2. Gene
  3. Spint1 - serine protease inhibitor, Kunitz type 1 Gene

Spint1 - serine protease inhibitor, Kunitz type 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as HAI-1

Gene ID: 20732 | Gene type: protein coding

About Spint1

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within extracellular matrix organization; neural tube closure; and placenta development. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; genitourinary system; and sensory organ. Orthologous to human SPINT1 (serine peptidase inhibitor, Kunitz type 1). [provided by Alliance of Genome Resources, Apr 2022]

Spint1 Products(3)

mRNA Protein Name
NM_001412660.1 NP_001399589.1 kunitz-type protease inhibitor 1 precursor
NM_001412661.1 NP_001399590.1 kunitz-type protease inhibitor 1 precursor
NM_016907.3 NP_058603.2 kunitz-type protease inhibitor 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: Inferred from mutant phenotype
17174946 MGI
acts upstream of or within embryonic placenta development IMP
IMP: Inferred from mutant phenotype
15964823 MGI
acts upstream of or within extracellular matrix organization IMP
IMP: Inferred from mutant phenotype
17174946 MGI
acts upstream of or within neural tube closure IGI
IGI: Inferred from genetic interaction
19592578 MGI
acts upstream of or within placenta blood vessel development IMP
IMP: Inferred from mutant phenotype
17174946 MGI
Cellular Component GO Annotation Evidence Reference Source
located in plasma membrane IDA
IDA: Inferred from direct assay
25758223 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kunitz-type protease inhibitor 1

hepatocyte growth factor activator inhibitor type 1

Recombinant Spint1 Proteins

Cat. No. Product Name Accession Purity
HY-P73092 HAI-1 Protein, Mouse (Fc) Q9R097 (E30-E443) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13685 SPINT1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spint1 NCBI NCBI:6692