2. Gene
  3. EVI2B - ecotropic viral integration site 2B Gene

EVI2B - ecotropic viral integration site 2B Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EVDB; CD361; D17S376

Gene ID: 2124 | Gene type: protein coding

About EVI2B

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:31,303,770-31,314,054 (from NCBI)

This gene has 2 transcripts (splice variants) and 89 orthologues. Broad expression in lymph node (RPKM 78.2), spleen (RPKM 77.3) and 15 other tissues.

Summary

Involved in positive regulation of granulocyte differentiation. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

EVI2B Products(1)

mRNA Protein Name
NM_006495.4 NP_006486.3 protein EVI2B precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of granulocyte differentiation IMP
IMP: Inferred from mutant phenotype
28186500 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein EVI2B

EVI-2B

Related Diseases

Diseases Alias
Chromosome 17q11.2 Deletion Syndrome

Nf1 Microdeletion Syndrome

17q11 Microdeletion Syndrome

Neurofibromatosis Type 1 Microdeletion Syndrome

Van Asperen Syndrome

Del(17)(Q11)

Monosomy 17q11

Chromosome 17q11.2 Deletion Syndrome, 1.4mb
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04575 EVI2B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus EVI2B MGD MGI:1890682
Felis catus EVI2B VGNC VGNC:98949
Canis familiaris EVI2B VGNC VGNC:53237
Rattus norvegicus EVI2B RGD RGD:6495961
Bos taurus EVI2B VGNC VGNC:55822