Il20rb - interleukin 20 receptor beta Gene

Mus musculus

Also known as Fndc6; Gm186; Il20R2

Gene ID: 213208 | Gene type: protein coding

About Il20rb

Summary

Enables interleukin-20 binding activity. Acts upstream of or within several processes, including negative regulation of T cell proliferation; negative regulation of type IV hypersensitivity; and regulation of cytokine production. Predicted to be integral component of plasma membrane. Is expressed in foregut; male reproductive gland or organ; metanephros; skin; and thymus. Orthologous to human IL20RB (interleukin 20 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Il20rb Products(1)

mRNA	Protein	Name
NM_001033543.3	NP_001028715.2	interleukin-20 receptor subunit beta precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables interleukin-20 binding	IPI IPI: Inferred from physical interaction	21844205	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within CD8-positive, alpha-beta T cell homeostasis	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within T cell homeostasis	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of T cell proliferation	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within homeostasis of number of cells within a tissue	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within immune response-inhibiting signal transduction	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within inflammatory response to antigenic stimulus	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of interleukin-10 production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of interleukin-2 production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of interleukin-4 production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within negative regulation of T cell proliferation	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within negative regulation of interleukin-2 production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within negative regulation of type II interferon production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within negative regulation of type IV hypersensitivity	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within positive regulation of interleukin-10 production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within positive regulation of interleukin-4 production	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of or within regulation of T cell activation	IMP IMP: Inferred from mutant phenotype	19124723	MGI
acts upstream of type II interferon production	IMP IMP: Inferred from mutant phenotype	19124723	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

interleukin-20 receptor subunit beta

fibronectin type III domain containing 6

Recombinant Il20rb Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76429	IL-20R beta Protein, Mouse (HEK293, His)	E9Q9A6/NP_001028715 (V27-S225)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06733	IL20RB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Il20rb	NCBI	NCBI:53833

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