Rnpep - arginyl aminopeptidase (aminopeptidase B) Gene

Mus musculus

Gene ID: 215615 | Gene type: protein coding

About Rnpep

Chromosome 1: 135,190,450-135,211,822 reverse strand.GRCm39:CM000994.3

This gene has 9 transcripts (splice variants), 156 orthologues, 10 paralogues and is associated with 1 phenotype. Ubiquitous expression in duodenum adult (RPKM 45.6), large intestine adult (RPKM 34.3) and 28 other tissues.

Summary

Predicted to enable metalloaminopeptidase activity; peptide binding activity; and transition metal ion binding activity. Predicted to be involved in negative regulation of blood pressure and proteolysis. Predicted to be located in several cellular components, including Golgi apparatus; external side of plasma membrane; and secretory granule. Predicted to be active in extracellular space. Is expressed in central nervous system and sensory organ. Orthologous to human RNPEP (arginyl Aminopeptidase). [provided by Alliance of Genome Resources, Apr 2022]

Rnpep Products(2)

mRNA	Protein	Name
NM_001159624.1	NP_001153096.1	aminopeptidase B isoform 2
NM_145417.3	NP_663392.2	aminopeptidase B isoform 1

Rnpep Protein Structure

M1_LTA4H

Leuk-A4-hydro_C

0
100
200
300
400
500
600
650 a.a.

Protein Preferred Names

Protein Names

aminopeptidase B

AP-B	arginine aminopeptidase
cytosol aminopeptidase IV

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12104	RNPEP Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12105	Rnpep Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12106	Rnpep Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Rnpep	NCBI	NCBI:6051

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