1. Gene
  2. Tgfa - transforming growth factor alpha Gene

Tgfa - transforming growth factor alpha Gene

Mus musculus

Also known as wa1; wa-1

Gene ID: 21802 | Gene type: protein coding

About Tgfa

Summary

This gene encodes a member of the epidermal growth factor (EGF) family of proteins that regulate cellular proliferation. The encoded protein undergoes proteolytic processing to generate a soluble glycoprotein that is secreted by the cell. The secreted protein binds to the EGF receptors to initiate signaling events resulting in cellular proliferation, mucous production or inhibition of gastric acid secretion. The transgenic expression of the encoded protein in mice induces the development of cancers in various tissues such as liver, pancreas, skin and mammary glands. Mice lacking the encoded protein exhibit a wavy coat and curly whiskers phenotype as well as abnormalities in the eye. [provided by RefSeq, Sep 2015]

Tgfa Products(2)

mRNA Protein Name
NM_001403118.1 NP_001390047.1 protransforming growth factor alpha isoform 2 preproprotein
NM_031199.5 NP_112476.1 protransforming growth factor alpha isoform 1 preproprotein
Protein Preferred Names Protein Names

protransforming growth factor alpha

Recombinant Tgfa Proteins

Cat. No. Product Name Accession Purity
HY-P77857 TGF alpha/TGFA Protein, Mouse (HEK293, Fc) P48030 (V39-A88) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Tgfa NCBI NCBI:7039