2. Gene
  3. GSX1 - GS homeobox 1 Gene

GSX1 - GS homeobox 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as GSH1; Gsh-1

Gene ID: 219409 | Gene type: protein coding

About GSX1

Cytogenetic location: 13q12.2 Genomic coordinates (GRCh38): 13:27,792,483-27,794,768 (from NCBI)

This gene has 1 transcript (splice variant), 159 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Enables sequence-specific double-stranded DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

GSX1 Products(1)

mRNA Protein Name
NM_145657.3 NP_663632.1 GS homeobox 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11731616 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11731616 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GSX1 Protein Structure

Homeobox

Homeobox: Homeobox domain (148 - 204)

  • 0
  • 100
  • 200
  • 264 a.a.
Protein Preferred Names Protein Names

GS homeobox 1

GS homeo box protein 1

GSX1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
GSX1 Q9H4S2 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Prey Pooling
32296183
Intra
GSX1 Q9H4S2 KRTAP19-7 Homo sapiens Q3SYF9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05890 GSX1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris GSX1 VGNC VGNC:41538
Macaca mulatta GSX1 VGNC VGNC:73203
Mus musculus GSX1 MGD MGI:95842
Felis catus GSX1 VGNC VGNC:102219
Rattus norvegicus GSX1 RGD RGD:1310020