2. Gene
  3. Cd70 - CD70 antigen Gene

Cd70 - CD70 antigen Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Cd27l; CD27LG; Tnfsf7; Tnlg8a

Gene ID: 21948 | Gene type: protein coding

About Cd70

Summary

Predicted to enable cytokine activity and Protease binding activity. Predicted to be involved in several processes, including B cell proliferation; T cell mediated immunity; and extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in Meckel's cartilage; hip; and skeleton. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd70 Products(1)

mRNA Protein Name
NM_011617.2 NP_035747.1 CD70 antigen
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables receptor ligand activity IDA
IDA: Inferred from direct assay
9366422 MGI
Biological Process GO Annotation Evidence Reference Source
involved in T cell proliferation IDA
IDA: Inferred from direct assay
9366422 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
9366422 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD70 antigen

CD27 ligand

CD27-L

Ki-24 antigen

tumor necrosis factor ligand 8a

tumor necrosis factor ligand superfamily member 7

Recombinant Cd70 Proteins

Cat. No. Product Name Accession Purity
HY-P72741 CD70 Protein, Mouse (HEK293, His) Q05A52 (Q47-P195) ≥95%
HY-P72928 CD70 Protein, Mouse (HEK293, mFc) Q05A52 (Q47-P195) ≥95%
HY-P72741AF Animal-Free CD70 Protein, Mouse (His) Q05A52 (Q47-P195) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-160649 MC-Gly-Gly-Phe-Gly-GABA-Exatecan Inhibitor 99.72% Unkown
HY-RS02264 CD70 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd70 NCBI NCBI:970
Macaca fascicularis Cd70 NCBI NCBI:102130438
Rattus norvegicus Cd70 NCBI NCBI:301132