2. Gene
  3. ARMC3 - armadillo repeat containing 3 Gene

ARMC3 - armadillo repeat containing 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CT81; KU-CT-1

Gene ID: 219681 | Gene type: protein coding

About ARMC3

Cytogenetic location: 10p12.2 Genomic coordinates (GRCh38): 10:22,928,053-23,038,523 (from NCBI)

This gene has 13 transcripts (splice variants), 195 orthologues and 4 paralogues. Restricted expression toward testis (RPKM 12.8).

Summary

Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).[supplied by OMIM, Mar 2008]

ARMC3 Products(4)

mRNA Protein Name
NM_001282745.2 NP_001269674.1 armadillo repeat-containing protein 3 isoform 2
NM_001282746.2 NP_001269675.1 armadillo repeat-containing protein 3 isoform 3
NM_001282747.2 NP_001269676.1 armadillo repeat-containing protein 3 isoform 4
NM_173081.5 NP_775104.2 armadillo repeat-containing protein 3 isoform 1

ARMC3 Protein Structure

Arm

Arm: Armadillo/beta-catenin-like repeat (57 - 89)

HEAT_2

HEAT_2: HEAT repeats (152 - 245)

HEAT_2

HEAT_2: HEAT repeats (276 - 381)

Arm

Arm: Armadillo/beta-catenin-like repeat (387 - 426)

Arm

Arm: Armadillo/beta-catenin-like repeat (471 - 503)

EDR1

EDR1: Ethylene-responsive protein kinase Le-CTR1 (737 - 859)

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  • 872 a.a.
Protein Preferred Names Protein Names

armadillo repeat-containing protein 3

beta-catenin-like protein

Related Diseases

Diseases Alias
Macular Degeneration, Age-Related, 4

Age Related Macular Degeneration 4

ARMD4

Macular Degeneration, Age-Related, Type 4
Currarino Syndrome

Currarino Triad

Partial Sacral Agenesis With Intact First Sacral Vertebra, Presacral Mass And Anorectal Malformation

CURRAS
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01002 ARMC3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ARMC3 MGD MGI:1918132
Bos taurus ARMC3 VGNC VGNC:26157
Rattus norvegicus ARMC3 RGD RGD:2319961
Canis familiaris ARMC3 VGNC VGNC:38125
Macaca mulatta ARMC3 VGNC VGNC:69932
Felis catus ARMC3 VGNC VGNC:59932