ZSCAN25 - zinc finger and SCAN domain containing 25 Gene

Homo sapiens

Also known as ZNF498

Gene ID: 221785 | Gene type: protein coding

About ZSCAN25

This gene has 10 transcripts (splice variants), 88 orthologues and 31 paralogues. Ubiquitous expression in small intestine (RPKM 5.1), duodenum (RPKM 3.7) and 25 other tissues.

Summary

This gene encodes a protein that bears some similarity to zinc finger proteins, which are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants have been identified, but the full-length nature for most of them has not been determined. [provided by RefSeq, Jul 2008]

ZSCAN25 Products(9)

mRNA	Protein	Name
NM_001350979.2	NP_001337908.1	zinc finger and SCAN domain-containing protein 25 isoform a
NM_001350980.2	NP_001337909.1	zinc finger and SCAN domain-containing protein 25 isoform a
NM_001350981.2	NP_001337910.1	zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350982.2	NP_001337911.1	zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350983.2	NP_001337912.1	zinc finger and SCAN domain-containing protein 25 isoform b
NM_001350984.2	NP_001337913.1	zinc finger and SCAN domain-containing protein 25 isoform c
NM_001350985.2	NP_001337914.1	zinc finger and SCAN domain-containing protein 25 isoform c
NM_001350986.2	NP_001337915.1	zinc finger and SCAN domain-containing protein 25 isoform d
NM_145115.3	NP_660090.2	zinc finger and SCAN domain-containing protein 25 isoform a

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZSCAN25 Protein Structure

SCAN

zf-C2H2

zf-H2C2_2

0
100
200
300
400
500
544 a.a.

Protein Preferred Names

Protein Names

zinc finger and SCAN domain-containing protein 25

zinc finger protein 498

Related Diseases

Diseases

Alias

Hypertension, Essential

Essential Hypertension	Hypertension
High Blood Pressure	Hypertension, Essential, Susceptibility To
Hypertensive Disease	Primary Hypertension
EHT	Hypertension, Salt-Sensitive Essential, Susceptibility To
Hyperpiesia	Idiopathic Hypertension
Hypertensive Disorder	Hypertension, Essential, Susceptibility To, 3
Hypertension, Essential 3	Hypertension, Essential, Salt-Sensitive
Hypertension, Essential, Susceptibility To, 6	Hypertension, Essential 6
Hypertension, Salt-Sensitive Essential	Hypertension, Susceptibility To
Hypertension, Essential, Susceptibility To, 4	Hypertension, Essential 4
Hypertension, Essential, Susceptibility To, 2	Hypertension, Essential 2
Hypertension, Essential, Susceptibility To, 1	Hypertension, Essential 1
Hypertension, Essential, Susceptibility To, 5	Hypertension, Essential 5
Htn	Vascular Hypertensive Disorder
Systemic Primary Arterial Hypertension	Hbp - [High Blood Pressure]
Systemic Arterial Hypertensive Disorder	Elevated Blood Pressure
Arterial Hypertension Nos	Hypertension Nos
Benign Hypertension	Systemic Arterial Hypertension
Systemic Hypertension	Artery Htn
Benign Htn	Vascular Htn
Vascular Hypertension	Cholesterol Hypertension
Cholesterol Htn	Idiopathic Htn
Malignant Hypertension	Malignant Htn
Raised Blood Pressure	Cardiovascular Hypertension
Primary Htn - [Hypertension]	High Arterial Tension
High Blood Pressure Disorder	Ht - [Hypertension]
Htn - [Hypertension]	Hypertensive Vascular Disease
Hypertensive Vascular Degeneration

Avoidant Personality Disorder

Anxious Personality Disorder

Personality Disorders

Pituitary Adenoma 1, Multiple Types

Pituitary Adenoma Predisposition	PITA1
Isolated Familial Somatotropinoma	Fis
Ifs	Somatotrophinoma, Familial
Acromegaly Due To Pituitary Adenoma 1	Pagh1
Pituitary Adenoma 1	Somatotropinoma, Familial Isolated
Somatotropic Adenoma	Somatotropinoma
Pituitary Gigantism	Hypophyseal Gigantism
Infantile And Juvenile Forms Of Acromegaly	Acromegaly Due To Pituitary Adenoma
Familial Isolated Pituitary Adenoma	Familial Isolated Somatotropinomas
Familial Somatotrophinoma	Fipa
Pituitary Adenoma, Growth Hormone-Secreting, 1	Gigantism Pituitary
Pituitary Adenoma, Type 1, Multiple Types	Gigantism
Pituitary Adenoma, Familial Isolated	Multiple Gastrointestinal Atresias

Expressive Language Disorder

Developmental Expressive Language Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16201	ZSCAN25 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ZSCAN25	MGD	MGI:3647079
Canis familiaris	ZSCAN25	VGNC	VGNC:48852
Macaca mulatta	ZSCAN25	VGNC	VGNC:79344
Rattus norvegicus	ZSCAN25	RGD	RGD:1308619

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