2. Gene
  3. MMD2 - monocyte to macrophage differentiation associated 2 Gene

MMD2 - monocyte to macrophage differentiation associated 2 Gene

  • Gene
  • Protein
  • Agent
Homo sapiens

Also known as PAQR10

Gene ID: 221938 | Gene type: protein coding

About MMD2

Summary

This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to Bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]

MMD2 Products(3)

mRNA Protein Name
NM_001100600.2 NP_001094070.1 monocyte to macrophage differentiation factor 2 isoform 1
NM_001270375.2 NP_001257304.1 monocyte to macrophage differentiation factor 2 isoform 3
NM_198403.4 NP_940685.3 monocyte to macrophage differentiation factor 2 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein kinase activity IDA
IDA: Inferred from direct assay
21968647 GOA
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of Ras protein signal transduction IDA
IDA: Inferred from direct assay
21968647 GOA
involved in positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
21968647 GOA
involved in positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
21968647 GOA
involved in regulation of protein localization IDA
IDA: Inferred from direct assay
21968647 GOA
Cellular Component GO Annotation Evidence Reference Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
22339580 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
22500632 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

monocyte to macrophage differentiation factor 2

monocyte-to-macrophage differentiation-associated protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08512 MMD2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown