2. Gene
  3. Vtn - vitronectin Gene

Vtn - vitronectin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Vn

Gene ID: 22370 | Gene type: protein coding

About Vtn

Summary

Enables extracellular matrix binding activity. Involved in oligodendrocyte differentiation. Acts upstream of or within cell-matrix adhesion; extracellular matrix organization; and positive regulation of cell-substrate adhesion. Located in extracellular matrix. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; metanephros; and retina. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Orthologous to human VTN (vitronectin). [provided by Alliance of Genome Resources, Apr 2022]

Vtn Products(1)

mRNA Protein Name
NM_011707.2 NP_035837.1 vitronectin precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables extracellular matrix binding IDA
IDA: Inferred from direct assay
18757743 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell-matrix adhesion IDA
IDA: Inferred from direct assay
15728191 MGI
acts upstream of or within extracellular matrix organization IDA
IDA: Inferred from direct assay
18757743 MGI
involved in oligodendrocyte differentiation IDA
IDA: Inferred from direct assay
23155445 MGI
acts upstream of or within positive regulation of cell-substrate adhesion IDA
IDA: Inferred from direct assay
18757743 MGI
Cellular Component GO Annotation Evidence Reference Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
15728191 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vitronectin

S-protein

serum-spreading factor

Recombinant Vtn Proteins

Cat. No. Product Name Accession Purity
HY-P73484 Vitronectin Protein, Mouse (HEK293, His) P29788 (D20-K478) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15724 VTN Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vtn NCBI NCBI:7448