LAMB4 - laminin subunit beta 4 Gene

Homo sapiens

Gene ID: 22798 | Gene type: protein coding

About LAMB4

Cytogenetic location: 7q31.1 Genomic coordinates (GRCh38): 7:108,011,662-108,130,361 (from NCBI)

This gene has 8 transcripts (splice variants), 128 orthologues and 27 paralogues. Biased expression in skin (RPKM 11.6), placenta (RPKM 1.2) and 1 other tissue.

Summary

Predicted to be an extracellular matrix structural constituent. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to be located in basement membrane; extracellular region; and membrane. Predicted to be part of laminin complex. [provided by Alliance of Genome Resources, Apr 2022]

LAMB4 Products(4)

mRNA	Protein	Name
NM_001318046.2	NP_001304975.1	laminin subunit beta-4 isoform 1 precursor
NM_001318047.2	NP_001304976.1	laminin subunit beta-4 isoform 2 precursor
NM_001318048.2	NP_001304977.1	laminin subunit beta-4 isoform 3 precursor
NM_007356.3	NP_031382.2	laminin subunit beta-4 isoform 1 precursor

LAMB4 Protein Structure

Laminin_N

Laminin_EGF

0
300
600
900
1200
1500
1761 a.a.

Protein Preferred Names

Protein Names

laminin subunit beta-4

laminin beta-1-related protein

Related Diseases

Diseases

Alias

Diverticulitis

Diverticulitis Of Colon

Colonic Diverticular Disease	Diverticulitis, Colonic
Diverticular Disease Of Colon

Macular Degeneration, Age-Related, 13

Age Related Macular Degeneration 13	ARMD13
Macular Degeneration, Age-Related, 13, Susceptibility To	Macular Degeneration, Age-Related, Type 13

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07505	LAMB4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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